17-ketogenic steroid assay test

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  • Citation tools Download this article to citation manager Cohen Harold . 17-Ketogenic Steroid Excretion in Obese Children Before and After Weight Reduction Br Med J 1958; 1 :686
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    This failure to respond to metyrapone may be interpreted as evidence of impaired pituitary‑adrenal reserve. In view of the normal response to exogenous ACTH, the failure to respond to metyrapone is inferred to be related to a defect in the CNS‑pituitary mechanisms which normally regulate ACTH secretions. Presumably the ACTH secreting mechanisms of these individuals are already working at their maximal rates to meet everyday conditions and possess limited “reserve” capacities to secrete additional ACTH either in response to stress or to decreased cortisol levels occurring as a result of metyrapone administration.

    17-ketogenic steroid assay test

    17-ketogenic steroid assay test

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