Ecdysteroids a novel class of anabolic agents

Ecdysone is a steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone , which is secreted from the prothoracic glands . Insect molting hormones (ecdysone and its homologues) are generally called ecdysteroids . Ecdysteroids act as moulting hormones of arthropods but also occur in other related phyla where they can play different roles. In Drosophila melanogaster , an increase in ecdysone concentration induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form in polytene chromosomes. Recent findings in Chris Q. Doe lab have found a novel role of this hormone in regulating temporal gene transitions within neural stem cells. [1] Ecdysone and other ecdysteroids also appear in many plants mostly as a protection agent (toxins or antifeedants) against herbivorous insects. These phytoecdysteroids have been reputed to have medicinal value and are part of herbal adaptogenic remedies like Cordyceps , yet an ecdysteroid precursor in plants has been shown to have cytotoxic properties. [2] A pesticide sold with the name MIMIC has ecdysteroid activity, although its chemical structure has little resemblance to the ecdysteroids.

Q. I read your review of creatine online and found it very informational. I am wondering if you can share some information about the recent body-building supplement Ecdy Bolin. I have been using it for a couple months (both with creatine and also without). It is promoted as has other benefits aside from muscle-building, such as nerve function. Anyway, I would like to know if you feel this supplement is a safe and a quality addition and how you feel about it in general. At the moment, I am not using creatine, only Ecdy Bolin.
   A. An internet search reveals Ecdy Bolin has 100 mg of ecdysterone. I have not seen any human studies with Ecdy Bolin or ecdysterone, so I have no opinion on this supplement at this time.

Ecdysteroids a novel class of anabolic agents

ecdysteroids a novel class of anabolic agents

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