I weighed in this morning lbs lighter than i was last week. It's hard to tell if it was because of Detonate or if it was my dieting/intense cardio training I've been doing. However, I can say that after I started taking 2 pills in the morning I could really feel the stimulants kick in if I don't begin my workout until after 30 minutes. The jitters and focus really kicked in and the thermos really affected me during my workout. I do have to say however the appetite suppression is still about the same. I don't feel much of a suppression, but that doesn't really bother me cause I can fight the food cravings.