Nonsteroidal anti-inflammatory drugs and corticosteroids

"It's very frightening. There seems to be no safe treatment window" for NSAIDs once you've had a heart attack, said Anne-Marie Schjerning Olsen, a cardiologist at Copenhagen University Hospital Gentofte who, along with colleagues, reviewed the records of nearly 100,000 patients who had suffered a heart attack between 1997 and 2009. About 44 percent of them received at least one prescription for an NSAID. Among people who didn't take NSAIDs, Olsen says, the cardiovascular risk after a first heart attack declines rapidly during the first year. "After five to 10 years it's almost the same" as the general population, she says. But heart attack survivors who took any NSAID other than low-dose aspirin had a higher risk of having a second heart attack or dying. The overall death risk rose 59 percent one year after the heart attack and 63 percent five years after, she said. Similarly, the risk of coronary death or a second heart attack rose 30 percent one year after the initial heart attack and 41 percent five years after.

In some countries, phytoestrogenic plants have been used for centuries in the treatment of menstrual and menopausal problems, as well as for fertility problems. [53] Plants used that have been shown to contain phytoestrogens include Pueraria mirifica , [54] and its close relative, kudzu , [55] Angelica , [56] fennel and anise . [32] In a rigorous study, the use of one such source of phytoestrogen, red clover , has been shown to be safe, but ineffective in relieving menopausal symptoms [57] ( black cohosh is also used for menopausal symptoms, but does not contain phytoestrogens. [58] ) Panax Ginseng contains phytoestrogens and has been used for menopausal symptoms . [ citation needed ]

If you do take an over the counter pain medication, be sure to follow the directions closely. In general, ibuprofen (Advil, Motrin), naproxen sodium (Aleve) or ketoprofen (Orudis KT) are helpful for those suffering from a sports injury that results in pain, swelling, and inflammation. Generic brands work in the same way and must meet the same standards as the brand name equivalent, but cost less. Read and follow the label directions and don't take more than the recommended dose. Also, don't use any OTC drugs for more than 10 days, unless your doctor or pharmacist tells you it's OK to do so.

SOURCES: Byron Cryer, MD, spokesman, American Gastroenterological Association; associate professor of medicine, University of Texas Southwestern Medical Center, Dallas. Nieca Goldberg, MD, spokeswoman for the American Heart Association; chief of women's cardiac care, Lennox Hill Hospital, New York; author, Women Are Not Small Men: Lifesaving Strategies For Preventing And Healing Heart Disease In Women . John Klippel, MD, president and CEO, Arthritis Foundation, Atlanta. Scott Zashin, clinical assistant professor, University of Texas Southwestern Medical Center; author of Arthritis Without Pain . American College of Rheumatology web site. Arthritis Foundation web site. American Heart Association web site. American College of Gastroenterology web site. American Gastroenterological Association web site. American Academy of Family Physicians web site. American Academy of Allergy, Asthma, and Immunology web site.

Nonsteroidal anti-inflammatory drugs and corticosteroids

nonsteroidal anti-inflammatory drugs and corticosteroids

SOURCES: Byron Cryer, MD, spokesman, American Gastroenterological Association; associate professor of medicine, University of Texas Southwestern Medical Center, Dallas. Nieca Goldberg, MD, spokeswoman for the American Heart Association; chief of women's cardiac care, Lennox Hill Hospital, New York; author, Women Are Not Small Men: Lifesaving Strategies For Preventing And Healing Heart Disease In Women . John Klippel, MD, president and CEO, Arthritis Foundation, Atlanta. Scott Zashin, clinical assistant professor, University of Texas Southwestern Medical Center; author of Arthritis Without Pain . American College of Rheumatology web site. Arthritis Foundation web site. American Heart Association web site. American College of Gastroenterology web site. American Gastroenterological Association web site. American Academy of Family Physicians web site. American Academy of Allergy, Asthma, and Immunology web site.

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