Stanozolol fm 30ml

[0017] 在某些优选的实施方案中,本发明提供了VEGFR-2结合多肽,其包含SEQ ID NO:192-194中的任一个的氨基酸序列。 [0017] In certain preferred embodiments, the present invention provides a VEGFR-2 binding polypeptide comprising SEQ ID NO: any one of the amino acid sequence 192-194. 在包含SEQ IDNO:194的氨基酸序列的多肽的情况下,PEG部分或其它目标部分可以共价地结合到93位的半胱氨酸上。 Comprising SEQ IDNO: amino acid sequence of the polypeptide case 194, PEG moiety or other targeted moiety can be covalently bound to the cysteine ​​at position 93. PEG部分也可以共价键合到多肽的胺部分上。 PEG moiety may be covalently bonded to the amine portion of the polypeptide. 胺部分可以是,例如,在多肽的N-末端的伯胺,或存在于氨基酸(例如赖氨酸或精氨酸)中的胺基。 Amine moiety may be, for example, a primary amine at the N- terminus of a polypeptide, or in the presence of amino acids (. lysine or arginine) in the group. 在某些实施方案中,PEG部分结合到选自下组的多肽位置:a)N-末端;b)N-末端和大多数N-末端β链或β样链之间;c)位于与靶结合位点相对的多肽面上的环;d)C-末端和大多数C-末端β链或β样链之间;和e)C-末端。 In certain embodiments, PEG is coupled to the polypeptide part of a position selected from the group: a) N- terminus; between b) N- terminus and the most N- terminal β chain or β-like strand; c) located at the target binding site of the polypeptide opposite ring faces; between D) and the most C- terminal β chain or C- terminal β chain like; and E) C- terminus.

Stanozolol fm 30ml

stanozolol fm 30ml

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