Transdermal patches (adhesive patches placed on the skin) may also be used to deliver a steady dose through the skin and into the bloodstream. Testosterone-containing creams and gels that are applied daily to the skin are also available, but absorption is inefficient (roughly 10%, varying between individuals) and these treatments tend to be more expensive. Individuals who are especially physically active and/or bathe often may not be good candidates, since the medication can be washed off and may take up to six hours to be fully absorbed. There is also the risk that an intimate partner or child may come in contact with the application site and inadvertently dose himself or herself; children and women are highly sensitive to testosterone and can suffer unintended masculinization and health effects, even from small doses. Injection is the most common method used by individuals administering AAS for non-medical purposes. 
Some side effects associated with spinal puncture include bruising, bleeding, infections, headaches, and blood clots. Cortisone side effects may cause weight gain, water retention, hot flashes, mood swings or insomnia, and elevated blood sugar levels in people with diabetes. Epidural steroid injections can provide diagnostic and therapeutic benefits. ESIs have been endorsed by the North American Spine Society and the Agency for Healthcare Research and Quality of the Department of Health and Human Services. Discuss this procedure with your friendly and caring doctor at the Florida Spine Institute to determine whether it is the right treatment for you.