Clinical trials are research studies which are conducted to answer questions. They can test many things from new drugs, new combinations of drugs, already approved drugs being studied to treat patients in new or different ways or investigating novel approaches to treat specific patients in unique circumstances. Clinical trials are run under strict guidelines with specific criteria for eligibility. The Mass General Bone Marrow Transplant Program has a very active clinical research portfolio with investigational studies covering almost all aspects of transplant care. The ultimate goal of clinical research is to improve the outcomes for all of our patients. If you are eligible for a clinical trial, your physician will offer you the chance for participation. We will comprehensively review the logistics and purpose of the trial and also offer alternatives including the standard of care.